As part of the REMEDIES programme a new lab scale continuous drug substance filtration and washing unit has been developed by Alconbury Weston Ltd (AWL). The overall aim of this strand of the project is to develop active pharmaceutical ingredient (API) filtration, washing and drying strategies that reduce processing time and cost and minimise negative impact on API physical properties to render the API optimal for secondary processing into drug products. This presentation reports evaluation of the continuous filtration unit using paracetamol as a model candidate drug.
To investigate the functionality of the AWL unit with respect to API filtration, washing and drying and to understand how the chemical and physical properties of the API slurry interact with the process parameters as a basis for designing and improving API isolation processes....
Session: L9 - Cake Filtration VI - Novel Continuous Process Concepts
Day: 12 October 2016
Time: 13:00 - 14:15 h