Production of antibiotics in the pharmaceutical industry - Continuous filtration enables efficient increase in antibiotics production

D. Steidl, T. Ochel*, BHS-Sonthofen GmbH, Germany

Significant savings, greater yield and improved throughput – a pharmaceutical company enjoys various benefits after moving from traditional batch production to a continuous antibiotics manufacturing process. A key component that makes these improvements possible is the rotary pressure filter from BHS-Sonthofen.

A globally operating pharmaceutical company produces a highly efficient new drug based on the traditional batch process method. The success of the new product quickly exceeds internal sales forecasts after its introduction on the market. Therefore, the company soon launches a project to increase production. The drug rapidly develops into a blockbuster, calling for a production increase that more than doubles the previous capacity.

The entire production process is analyzed as part of the extension project towards implementing an efficient increase in production quantities as quickly as possible. Rather than simply copying the old production line, project management recommends modifying the batch process by introducing a continuously operating BHS rotary pressure filter (RPF) and adding new reactors.

The project implemented as a result of this assessment increases production in the order of 150 percent, while incurring only a fraction of the investment costs of the previous manufacturing process. In addition, changing to continuous filtration increases the yield by close to a third, further improving the profitability of the new process. The key to achieving these benefits is...

Session: L8 - Continuous Vacuum and Pressure Filters
Day: 14 March 2018
Time: 13:00 - 14:15 h

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